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Protein-associated DNA occupies about 1/4 of the intracellular volume forming a concentrated viscous phase with liquid crystalline properties, called the nucleoid.
At the bottom of the page there are also links to related topics at this level on the BioTopics website.
Proceedings of the National Academy of Sciences.It is important not to get condensation and hydrolysis muddled up, as they are in fact opposite processes! .Many features of the DNA double helix contribute to its large stiffness, including the mechanical properties of the sugar-phosphate backbone, electrostatic repulsion between phosphates (DNA bears on average one elementary negative charge per each.17 nm of the double helix stacking interactions between the bases.The products are simpler substances.1, dNA diameter is about 2 nm, while the length of a stretched single molecule may be up to several dozens of centimetres depending on the organism.Progress in Biophysics and Molecular Biology.
Once again this results in -O- bridges forming between the glycerol and each fatty acid chain.
In DNA replication, each new strand that forms is built up from nucleotides according to base pairing rules and joined by repeated condensation reactions.
The dilute-solution approximation is violated for two reasons.1 Physics of DNA condensation edit Condensation of long double-helical DNAs is a sharp phase transition, which takes place within a narrow interval of condensing agent f Since the double helices come very bon reduction zoo de la fleche closely to each other in the condensed phase, this leads to the.In Pharmaceutical perspectives of nucleic acid-based therapeutics.Maltase then completes the hydrolysis process, splitting each maltose molecule into two glucose molecules.Vijayanathan.; Thomas.; Thomas.Sucrase (also known as invertase) breaks down sucrose, producing glucose and fructose.Condensation - basic principles, the term monomer is given to single (smaller, simple) sub-units from which (larger, complex) molecular stuctures called polymers are built up by condensation.1 DNA condensation in bacteria edit Bacterial DNA is packed with the help of polyamines and proteins.Zimmerman, SB; Murphy, LD (1996).Lipases, lipases break ester bonds between glycerol and fatty acids, or phosphate groups.This topic has connections with other BioTopics units.2, in addition, DNA condensation has many potential applications in medicine and biotechnology.Condensed DNA often has surprising properties, which one would not predict from classical concepts of dilute solutions.Also do not assume that this breakdown releases energy, which is usually produced when the simpler substances are oxidised in respiration.
In nucleic acids, there is a similar but somewhat more complex situation.
Joining two -OH groups with the removal of H2O results in a disaccharide containing an -O- bridge between the 2 monosaccharide units.